6515015673227, 6515-01-567-3227, NWK-GPX01, 6515-01-567-3227 - GLUTATHIONE PEROXID

Part Details | GLUTATHIONE PEROXID

6515-01-567-3227

Alternate Parts: NWKGPX01, NWK-GPX01, 6515-01-567-3227, 01-567-3227, 6515015673227, 015673227

Supply Group (FSG)	NSN Assigned	NIIN	Item Name Code (INC)

REFERENCE DRAWINGS & PICTURES

Cross Reference | NSN 6515-01-567-3227

Part Number	Cage Code	Manufacturer
NWK-GPX01	4SM76	NORTHWEST LIFE SCIENCE SPECIALTIESLLC

Technical Data | NSN 6515-01-567-3227

Characteristic	Specifications
SPECIAL FEATURES	GLUTATHIONE PEROXIDASE (GPX) (EC 1.11.1.9) ENZYMES BELONG TO A FAMILY OF SELENOPROTEINS WHOSE FUNCTION IS TO CATALYZE THE REDUCTION OF VARIOUS PEROXIDES. FOUR TYPES OF GPX (GPX-1 TO 4) HAVE BEEN IDENTIFIED IN MAMMALIAN SPECIES. GPX-1 IS THE CLASSIC INTRACELLULAR FORM WHILE GPX-2, GPX-3 AND GPX-4 ARE GASTROINTESTINAL, PLASMA AND PHOSPHOLIPID HYDROPEROXIDASE FORMS; RESPECTIVELY. THREE OF THE FORMS ARE TETRAMERS COMPOSED OF 4 IDENTICAL 22 KDA MONOMERS WHILE GPX-4 IS MONOMERIC. THE MONOMERIC SUBUNITS OF GPX-1 TO 3 EACH HAVE THE AMINO ACID SELENOCYSTEIN AT THE ACTIVE SITE OF THE ENZYME. THE BEST CHARACTERIZED AND MOST HEAVILY RESEARCHED FORM IS GPX-1, THE INTRACELLULAR FORM, SOMETIMES ALSO CALLED CELLULAR GPX (CGPX).

Characteristic

Specifications

SPECIAL FEATURES

GLUTATHIONE PEROXIDASE (GPX) (EC 1.11.1.9) ENZYMES BELONG TO A FAMILY OF SELENOPROTEINS WHOSE FUNCTION IS TO CATALYZE THE REDUCTION OF VARIOUS PEROXIDES. FOUR TYPES OF GPX (GPX-1 TO 4) HAVE BEEN IDENTIFIED IN MAMMALIAN SPECIES. GPX-1 IS THE CLASSIC INTRACELLULAR FORM WHILE GPX-2, GPX-3 AND GPX-4 ARE GASTROINTESTINAL, PLASMA AND PHOSPHOLIPID HYDROPEROXIDASE FORMS; RESPECTIVELY. THREE OF THE FORMS ARE TETRAMERS COMPOSED OF 4 IDENTICAL 22 KDA MONOMERS WHILE GPX-4 IS MONOMERIC. THE MONOMERIC SUBUNITS OF GPX-1 TO 3 EACH HAVE THE AMINO ACID SELENOCYSTEIN AT THE ACTIVE SITE OF THE ENZYME. THE BEST CHARACTERIZED AND MOST HEAVILY RESEARCHED FORM IS GPX-1, THE INTRACELLULAR FORM, SOMETIMES ALSO CALLED CELLULAR GPX (CGPX).